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Pregnancy Loss - Valid Insights

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Reasons for Recurrent Pregnancy Loss

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Product of Conception Testing

POC testing is typically done to provide answers for couples who have experienced pregnancy loss and to help guide future reproductive decisions.

Comprehensive Genetic Testing Solutions in Product Of Conception

QF PCR - 5 Chromosomes 
Detects aneuploidies in chromosome 13,18,21, X and Y
QF PC Extended - 8 Chromosomes
Detects aneuploidies in chromosome 13,15, 16,18,21, 22, X and Y
POC Karyotyping
POC Karyotyping
Molecular Karyotyping by NGS
Detection of gain or loss in whole chromosome - all 23 pairs
POC Microarray
POC Microarray
Microarray 315k 
315,000 markers Whole -chromosome aneuploidies. Submicroscopic gains (> 2 Mb) and losses (> 1 Mb) & Triploidy
Microarray 750k 
750,000 markers Whole-chromosome aneuploidies Submicroscopic gains (> 400kb) and losses (> 100kb) & Triploidy
POC Mutation Testing
POC Mutation Testing
Clinical Exome Sequencing 
Detects mutations across 6500 genes
Whole Exome Sequencing 
Detects mutation on 22,000 genes
DNA Storage
POC DNA Banking
DNA Storage 
Fetal DNA storage allows access to diagnostic tests in fetal sample at a later point of time
POC Pathological Analysis
POC Pathological Analysis
Fetal Autopsy 
In dept pathological analysis of fetal anomalies
Placental study 
Detailed analysis of placental pathology

Indications of POC Testing

  • Recurrent spontaneous abortions
  • Abnormal Ultrasound findings
  • Intrauterine growth retardation
  • Abnormal prenatal screening results
  • Pregnancy loss after ART conception
  • Bad Obstetric History
  • Advanced maternal age
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Hope is Here

Schedule a consultation today and let our experienced team guide you through the process of Product of Conception Testing. Together we can understand, take action, and renew hope
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Parental investigations in RPL

Parental investigations in RPL are an important step in identifying potential causes of recurrent pregnancy loss and can help couples make informed decisions about their options for fertility treatments.

Hormone Testing
Hormone testing can help identify any hormonal imbalances that may be contributing to RPL. Tests may include levels of follicle-stimulating hormone (FSH), luteinizing hormone (LH), thyroid-stimulating hormone (TSH), and progesterone.
Ultrasound can be used to evaluate the uterus and ovaries to identify any structural abnormalities that may be contributing to RPL. This may include abnormalities such as uterine fibroids, polyps, or a septum.
Genetic Testing
Genetic testing may be conducted to identify any genetic abnormalities that may be contributing to RPL. This may include karyotyping for the couple.
Immunological testing
Immunological testing may be conducted to identify any autoimmune disorders that may be contributing to RPL, such as antiphospholipid syndrome or lupus.
Thrombophilia Testing
Thrombophilia testing may be conducted to identify any clotting disorders that may be contributing to RPL, such as Factor V Leiden or protein C or S deficiency.
Endometrial Evaluations
An endometrial biopsy involves removing a small sample of the uterine lining for examination under a microscope to identify any abnormalities in the endometrium that may be contributing to RPL.

Parental investigations in RPL typically involve chromosomal analysis of both parents to identify any structural or numerical chromosomal abnormalities. This can be done by karyotyping.

Karyotyping involves analyzing a sample of cells from each parent’s blood or other tissues to examine the chromosomes for any abnormalities such as missing or extra chromosomes, or rearrangements of chromosome segments

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