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PGT-A (PGS)

(Preimplantation Genetic Testing - Aneuploidy)

Enabling your fertility
specialist to choose a
genetically healthy embryo.

Normal embryos carry 23 pairs of chromosomes. An imbalance in chromosome numbers i.e. the presence of extra or missing chromosomes has been implicated to be among the most common causes of implantation failure or miscarriages. Embryos carrying abnormal chromosome numbers occur frequently in infertile couples. Preimplantation Genetic Testing (PGT-A (PGS)) is a genetic test performed on embryos to determine if the embryo is carrying normal number of chromosomes. The chromosomally abnormal embryos are screened can select genetically healthy embryos can be transferred. This increases the chances of attaining a healthy pregnancy and reduces risk of miscarriages.

Closeup shot of 3d DNA structure with two linked strands.

When is PGT-A (PGS)
Recommended

Patients undergoing the IVF process can opt for PGT-A (PGS). In fact, chromosome screening is an add-on, as about 50% of IVF derived embryos are known to carry chromosome abnormalities.

Studies suggest that women with advanced age and repeated implantation failure are at a higher risk of producing chromosomally abnormal embryos.

PGT-A (PGS) is also recommended for patients diagnosed with male factor infertility, specifically when sperm samples are reported to carry abnormal chromosome numbers

PGT-A (PGS) is recommended for Idiopathic infertility (cases where doctors are unable to conclude any apparent reason for infertility), several miscarriages or failed IVF attempts.

PGT-A (PGS) Process

PGT-A (PGS) Services

Genetic counselling on the probability of developing or transmitting chromosomal abnormalities in embryos

EMBRYO BIOPSY
Day 3 - Frozen Embryo Transfer
Day 5 - Frozen Embryo Transfer

Embryo Biopsy followed by
NGS-based PGT-A (PGS) for aneuploidy of all 22 pairs of chromosomes

Accurate, reproducible and rapid testing
by Next Generation Sequencing (NGS)

15 Hours automated NGS Protocol

Embryo biopsy assistance and validation

Wholly owned cold chain logistics

Planned elective single embryo transfer (SET)

Can be combined with PGT-M (PGD) cycle

Benefits

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PGT-A (PGS) reduces miscarriage rates as only chromosomally normal embryos are selected for transfer.
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The chance of increasing the pregnancy rate is very much considerable.

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The embryos can be transferred with utmost confidence as the genetically unhealthy embryos have already been excluded.

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