CYSTIC FIBROSIS (CF)

CF is caused by mutations in the CFTR gene and causes altered properties of secretions as a result of altered chloride transport. Lung and pancreatic functions are affected and long term prognosis is significantly improved by early commencement of physiotherapy and antibiotic treatment. Several blood biomarkers are available but immunoreactive trypsin (IRT) measurement with immunoassay is most widely used

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